Liên kết ngoài Axit_fumaric

Liên kết ngoài Axit_fumaric

International Chemical Safety Card 1173

x t s Chu trình Krebs
			Oxaloacetic acid			Axit malic			Fumaric acid			Axit succinic			Succinyl-CoA


Acetyl-CoA			NADH + H+	NAD+		H2O	FADH2	FAD	CoA + ATP(GTP)	Pi + ADP(GDP)
	+	H2O						NADH + H+ + CO2
		Coenzyme A			NAD+
					H2O		H2O			NAD(P)+	NAD(P)H + H+			CO2


			Citrate			cis-Aconitic acid			Isocitric acid			Oxalosuccinic acid			Alpha-Ketoglutaric acid

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Con đường chuyển hóa của chu trình ure

			L-citrulline		Carbamoyl phosphate	L-ornithine
				Pi

L-aspartate					Urea
	+	ATP
PPi	+	AMP			H2O



			L-argininosuccinate		Fumarate	L-arginine

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Chất trung gian chuyển hóa axit amin

lysine→	Saccharopine • Allysine • Axit α-aminoadipic • α-cetoadipate • Glutaryl-CoA • Glutaconyl-CoA • Crotonyl-CoA • β-Hydroxybutyryl-CoA
leucine→	Axit α-cetoisocaproic • Isovaleryl-CoA • 3-Methylcrotonyl-CoA • 3-Methylglutaconyl-CoA • HMG-CoA
tryptophan→alanine→	N'-Formylkynurenine • Kynurenine • Axit Anthranilic • 3-Hydroxykynurenine • Axit 3-Hydroxyanthranilic • 2-Amino-3-carboxymuconic semialdehyde • 2-Aminomuconic semialdehyde • Axit 2-Aminomuconic • Glutaryl-CoA

Đ→pyruvate→citrate

glycine→serine→	Axit 3-Phosphoglyceric • glycine→creatine: Glycocyamine • Phosphocreatine • Creatinine

Đ→glutamate→
α-cetoglutarate

histidine→	Axit Urocanic • Axit Imidazol-4-one-5-propionic • Axit Formiminoglutamic • Glutamate-1-semialdehyde
proline→	Axit 1-Pyrroline-5-carboxylic
arginine→	Ornithine • Putrescine • Agmatine
khác	cysteine+glutamate→glutathione: γ-Glutamylcysteine

Đ→propionyl-CoA→
succinyl-CoA

valine→	Axit α-Cetoisovaleric • Isobutyryl-CoA • Methacrylyl-CoA • 3-Hydroxyisobutyryl-CoA • Axit 3-Hydroxyisobutyric • Axit 2-Methyl-3-oxopropanoic
isoleucine→	Axit 2,3-Dihydroxy-3-methylpentanoic • 2-Methylbutyryl-CoA • Tiglyl-CoA • 2-Methylacetoacetyl-CoA
methionine→	tạo homocysteine: S-Adenosyl methionine • S-Adenosyl-L-homocysteine • Homocysteine • chuyển hóa thành cysteine: Cystathionine • Axit alpha-Cetobutyric+Cysteine
threonine→	Axit α-Cetobutyric
propionyl-CoA→	Methylmalonyl-CoA

phenylalanine→tyrosine→	Axit 4-Hydroxyphenylpyruvic • Axit Homogentisic • 4-Maleylacetoacetate

Đ→oxaloacetate

xem chu trình ure

Khác

Chuyển hóa cysteine	Axit Cysteine sulfinic

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Liên quan

Axit Axit clohidric Axit deoxyribonucleic Axit acetic Axit ascobic Axit citric Axit Gamma-Hydroxybutyric Axit nitric Axit amin Axit sulfuhydric

Tài liệu tham khảo

WikiPedia: Axit_fumaric http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-b... http://chemapps.stolaf.edu/jmol/jmol.php?model=C(%... http://ecb.jrc.it/esis/index.php?GENRE=ECNO&ENTREE... http://www.genome.ad.jp/dbget-bin/www_bget?cpd:C00... http://www.whocc.no/atcddd/indexdatabase/index.php... http://www.commonchemistry.org/ChemicalDetail.aspx... http://www.inchem.org/documents/icsc/icsc/eics1173... http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHE...